The maximum sizing of the possible print area is defined by your printer. The Silhouette Studio program will technically allow you to define your media size and place registration marks on larger page sizes according to your printer's size restrictions.
The maximum cutting size is defined by your Silhouette cutting machine model.
If you have a Portrait model, then the maximum Print & Cut media size would be 8.5 x 11 inches.
If you have a Cameo (12") model, then the maximum Print & Cut material size would be 12 x 12 inches. Larger Cameo models can technically allow larger material sizes, but we recommend a maximum material size of 12 x 12 inches and to use a cutting mat in order to ensure proper Print & Cut registration alignment.
If you have a Curio model, then the maximum Print & Cut material size would depend on your machine base size. If using the default base included with the machine, then the maximum Print & Cut material size would be 8.5 x 6 inches. If using the large base (sold separately), then the maximum Print & Cut material size would be 8.5 x 11 inches.